Familial liability to schizophrenia and premorbid adjustment.
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Authors
Walshe, Muriel
Taylor, Mark
Schulze, Katja
Bramon, Elvira
Frangou, Sophia
Stahl, Daniel
Kravariti, Eugenia
Daly, Eileen
Fearon, Paul
Murray, Robin M
Issue Date
2007-Sep
Type
Journal Article
Language
en
Keywords
Alternative Title
Abstract
We assessed premorbid functioning during childhood and adolescence in 50 people with schizophrenia from multiply affected families, 39 of their unaffected siblings, 69 people with schizophrenia with no family history of psychosis, 67 of their unaffected siblings and 83 controls. People with schizophrenia had poorer premorbid social and academic adjustment and exhibited a decline between childhood and adolescence compared with controls. Unaffected siblings from multiply affected families also had poor academic functioning in adolescence, with a decline between childhood and adolescence. This may represent a familial (presumed genetic) effect.
Description
Citation
Walshe, M., Taylor, M., Schulze, K., Bramon, E., Frangou, S., Stahl, D., Kravariti, E., Daly, E., Fearon, P., Murray, R. M., & McDonald, C. (2007). Familial liability to schizophrenia and premorbid adjustment. The British journal of psychiatry : the journal of mental science, 191, 260–261. https://doi.org/10.1192/bjp.bp.106.033688
Publisher
License
Journal
The British journal of psychiatry : the journal of mental science
Volume
191
Issue
PubMed ID
ISSN
0007-1250