Effect of early intervention on 5-year outcome in non-affective psychosis.
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Authors
Gafoor, Rafael
Nitsch, Dorothea
McCrone, Paul
Craig, Tom K J
Garety, Philippa A
Power, Paddy
McGuire, Philip
Issue Date
2010-May
Type
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Language
en
Keywords
Alternative Title
Abstract
Early specialised care may improve short-term outcome in first-episode non-affective psychosis, but it is unclear if these benefits endure.
To assess the long-term effect of early intervention in psychosis.
Individuals with first-episode psychosis were randomised to specialised care or care as usual (trial number: ISRCTN73679874). Outcome after 5 years was assessed by case-note review.
There were no significant differences in the admission rate (coefficient 0.096, 95% CI -0.550 to 0.742, P = 0.770) or the mean number of bed days (coefficient 6.344, 95% CI -46 to 58.7, P = 0.810).
These findings that specialist intervention did not markedly improved outcome at 5 years accord with those from a larger OPUS study. The sample size of this study was small and these results should be generalised with caution. More research is needed.
To assess the long-term effect of early intervention in psychosis.
Individuals with first-episode psychosis were randomised to specialised care or care as usual (trial number: ISRCTN73679874). Outcome after 5 years was assessed by case-note review.
There were no significant differences in the admission rate (coefficient 0.096, 95% CI -0.550 to 0.742, P = 0.770) or the mean number of bed days (coefficient 6.344, 95% CI -46 to 58.7, P = 0.810).
These findings that specialist intervention did not markedly improved outcome at 5 years accord with those from a larger OPUS study. The sample size of this study was small and these results should be generalised with caution. More research is needed.
Description
Citation
Gafoor, R., Nitsch, D., McCrone, P., Craig, T. K., Garety, P. A., Power, P., & McGuire, P. (2010). Effect of early intervention on 5-year outcome in non-affective psychosis. The British journal of psychiatry : the journal of mental science, 196(5), 372–376. https://doi.org/10.1192/bjp.bp.109.066050
Publisher
License
Journal
The British journal of psychiatry : the journal of mental science
Volume
196
Issue
5
PubMed ID
ISSN
1472-1465