An Irish case of pulmonary emboli secondary to clozapine therapy.
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Authors
O'Luanaigh, Conor
Scully, Paul
Issue Date
2006-Mar
Type
Journal Article
Language
en
Keywords
Alternative Title
Abstract
Clozapine is the prototype atypical antipsychotic used for treatment-resistant schizophrenia, but its use has been limited by the well-established association with agranulocytosis. An increased risk of other serious adverse events such as myocarditis and thromboembolism has also been suggested to be associated with clozapine therapy.
We describe an Irish case of multiple pulmonary emboli detected by CT pulmonary angiogram thought to be secondary to clozapine therapy.
Although clozapine is a very efficacious antipsychotic its many side-effects limit its use. Pulmonary embolism must be remembered as a potential rare side-effect in clozapine therapy. Underlying mechanisms are still unclear although several have been proposed.
We describe an Irish case of multiple pulmonary emboli detected by CT pulmonary angiogram thought to be secondary to clozapine therapy.
Although clozapine is a very efficacious antipsychotic its many side-effects limit its use. Pulmonary embolism must be remembered as a potential rare side-effect in clozapine therapy. Underlying mechanisms are still unclear although several have been proposed.
Description
Citation
O'Luanaigh, C., & Scully, P. (2006). An Irish case of pulmonary emboli secondary to clozapine therapy. Irish journal of psychological medicine, 23(1), 36–37. https://doi.org/10.1017/S0790966700009472
Publisher
License
Journal
Irish journal of psychological medicine
Volume
23
Issue
1
PubMed ID
ISSN
2051-6967